![]() ![]() ![]() Chief limitations of the literature were the paucity of head-to-head comparisons between IPCDs in surgical and medical patients, and the identification of primarily asymptomatic DVTs of uncertain clinical importance. Overall, there were no consistent associations between specific brand-name IPCDs or sleeve location and ease of use or adherence. Subgroup analyses did not show significant differences by device location, mode of inflation, or risk of bias elements. Limited data suggest that concurrent use of anticoagulation with IPCD may lower the risk of VTE compared to anticoagulation alone (RR 0.27 95% CI 0.05 to 1.64) and that IPCD compared to anticoagulation may lower the risk of major bleeding (RR 0.33 95% CI 0.07 to 1.51). IPCDs were comparable to anticoagulation for major clinical outcomes (VTE: risk ratio 1.39 95% confidence interval, 0.73 to 2.64). One showed lower VTE rates for a VenaFlow ® compared to the Kendall SCD, but 2 other studies showed no difference between the PlexiPulse ® and the Kendall SCD. Peristaltic pneumatic compression will propel the fluid through the body mechanically allowing it to be excreted normally. Only 3 trials compared different IPCDs directly. Pneumatic Compression Device Pneumatic compression pumps are designed to assist in the moving of venous and lymphatic fluid when the vessels are impaired. The most commonly studied devices were the Kendall SCD™ and A-V Impulse System™. The methodological quality of the included studies was variable and generally suboptimal. Our review considered 3 types of evidence: 1) head-to-head comparisons of IPCDs 2) indirect comparisons of IPCDs to a common comparator ( eg, foot vs calf devices, each compared to anticoagulation) and 3) data on ease of use or adherence from patients or staff. Eighteen RCTs and 3 observational studies were eligible most were conducted in patients undergoing joint replacement surgery. ![]()
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